01 / The story

Retatrutide has been studied for activity at GLP-1, GIP and glucagon receptors. That three-part design is the core of the original GeneTune visual comparison.

02 / In plain language
01

GLP-1

One incretin route involved in appetite and glucose regulation.

02

GIP

A second incretin route in the metabolic model.

03

Glucagon

A third receptor target that changes the research question.

THE IDEA TO KEEPThree targets describe the design; they do not guarantee an outcome.
03 / Where the evidence stops
Human trial · Phase 2 publication

A published randomized Phase 2 obesity trial evaluated retatrutide. These selected original frames explain the receptor model; trial results and safety require their own careful reading.